2FF3
Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gelsolin | polymer | 150 | 16868.0 | 1 | UniProt (P06396) Pfam (PF00626) | Homo sapiens (human) | Actin-depolymerizing factor, ADF, Brevin, AGEL |
| 2 | B (C) | Neural Wiskott-Aldrich syndrome protein | polymer | 15 | 1455.5 | 1 | UniProt (O00401) | Homo sapiens (human) | N-WASP |
| 3 | C (B) | Actin, alpha skeletal muscle | polymer | 375 | 41862.6 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | Alpha-actin-1 |
| 4 | D, E, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | G (B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 6 | H, I, J (A, C, B) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A: 25 - 152 (UniProt: P06396)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | expression tag |
| Lys 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Val 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Arg 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| His 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60186.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 627.4 | |
| All* | Total formula weight | 60813.5 |
