2FA7

Crystal structure of the complex of bovine lactoferrin C-lobe with a pentasaccharide at 2.38 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lactotransferrin	polymer	345	37655.5	1	UniProt (P24627) Pfam (PF00405)	Bos taurus (cattle)	Lactoferrin
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C (C)	beta-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G39085UU)
4	D (D)	alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G05674CR)
5	E (E)	2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1034.0	1	In PDB GlyTouCan (G39751IR)
6	F (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	G, H, I (A)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
8	J (A)	FE (III) ION	non-polymer		55.8	1	Chemie (FE)
9	K (A)	CARBONATE ION	non-polymer		60.0	1	Chemie (CO3)
10	L (A)	water	water		18.0	275	Chemie (HOH)

Sequence modifications

A: 342 - 686 (UniProt: P24627)

PDB	External Database	Details
Lys 565	Asn 584	engineered mutation
Glu 608	Lys 627	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37655.5
Branched	Number of molecules	4
	Total formula weight	3442.2
Non-Polymers*	Number of molecules	6
	Total formula weight	408.1
All*	Total formula weight	41505.8

*Water molecules are not included.