2F99
Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Aklanonic Acid methyl Ester Cyclase, AknH | polymer | 153 | 17951.1 | 4 | GenBank (7800671) Pfam (PF07366) UniProt (by SIFTS) (O52646) In PDB | Streptomyces galilaeus | |
2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
3 | A, B, C, D | {3-[(1R,3S)-1,3-DIHYDROXYPENTYL]-4,5,9,10-TETRAHYDROXY-2-ANTHRYL}ACETATE | non-polymer | 414.4 | 4 | Chemie (AKV) | |||
4 | water | water | 18.0 | 459 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 144 (GenBank: 7800671)
PDB | External Database | Details |
---|---|---|
Met -8 | - | initiating methionine |
Ala -7 | - | cloning artifact |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Arg 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 71804.6 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 2714.3 | |
All* | Total formula weight | 74518.9 |