2F8N
2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (I, J) | alpha-satellite DNA (146 bp) | polymer | 146 | 45054.8 | 2 | Homo sapiens (human) | ||
| 2 | C, F (A, E) | Histone H3.1 | polymer | 136 | 15421.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 3 | D, G (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 4 | E (D) | Histone 3, H2ba | polymer | 126 | 14025.3 | 1 | UniProt (Q9D2U9) Pfam (PF00125) | Mus musculus (house mouse) | |
| 5 | H (H) | Histone H2B.1 | polymer | 123 | 13655.9 | 1 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 6 | I (G) | Core histone macro-H2A.1 | polymer | 120 | 12984.3 | 1 | UniProt (O75367) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | |
| 7 | J (K) | Histone H2A type 1 | polymer | 149 | 16198.8 | 1 | UniProt (Q8CGP6) Pfam (PF00125) Pfam (PF16211) | Mus musculus (house mouse) | |
| 8 | K, L, M, N, O... (I, J, A, B, D...) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
H: 1401 - 1522 (UniProt: P02281)
G: 1003 - 1122 (UniProt: O75367)
K: 0 - 129 (UniProt: Q8CGP6)
| PDB | External Database | Details |
|---|---|---|
| Met 1400 | - | initiating methionine |
| Thr 1429 | Ser 32 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1067 | Gly 64 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 200605.1 | |
| All* | Total formula weight | 200605.1 |
