2F8C
Crystal structure of FPPS in complex with Zoledronate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Farnesyl Diphosphate Synthase | polymer | 350 | 40183.9 | 1 | UniProt (P14324) Pfam (PF00348) In PDB | Homo sapiens (human) | FPP synthetase; FPS; Farnesyl pyrophosphate synthetase |
2 | F | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
3 | F | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
4 | F | ZOLEDRONIC ACID | non-polymer | 272.1 | 1 | Chemie (ZOL) | |||
5 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDB | External Database | Details |
---|---|---|
Gly 4 | - | cloning artifact |
Pro 5 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40183.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 440.0 | |
All* | Total formula weight | 40623.8 |