2F7D
A mutant rabbit cathepsin K with a nitrile inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin K | polymer | 215 | 23554.5 | 1 | UniProt (P43236) Pfam (PF00112) | Oryctolagus cuniculus (rabbit) | OC-2 protein |
| 2 | B (A) | (1R,2R)-N-(2-AMINOETHYL)-2-{[(4-METHOXYPHENYL)SULFONYL]METHYL}CYCLOHEXANECARBOXAMIDE | non-polymer | 354.5 | 1 | Chemie (NOQ) | |||
| 3 | C (A) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 1 - 211 (UniProt: P43236)
| PDB | External Database | Details |
|---|---|---|
| Asp 61 | Tyr 175 | engineered mutation |
| Leu 157 | Val 274 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23554.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 354.5 | |
| All* | Total formula weight | 23909.0 |
