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2F71

Protein tyrosine phosphatase 1B with sulfamic acid inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase, non-receptor type 1polymer29834720.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C, D, E, F
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4G
(A)
3-[3-(3(S)-METHYLCARBAMOYL-7-SULFOAMINO-3,4,-DIHYDRO-1H-ISOQUINOLIN-2-YL)-3-OXO-PROPYL]-BENZOIC ACIDnon-polymer461.51Chemie (UN7)
5H
(A)
waterwater18.0348Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34720.6
Non-Polymers*Number of molecules6
Total formula weight627.6
All*Total formula weight35348.2
*Water molecules are not included.

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PDB entries from 2025-07-30

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