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2F6Z

Protein tyrosine phosphatase 1B with sulfamic acid inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase, non-receptor type 1polymer29834720.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C, D, E, F
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4G
(A)
{3(S)-METHYLCARBAMOYL-2-[3-(3-SULFOAMINO-PHENYL)-PROPIONYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-7-YL}-SULFAMIC ACIDnon-polymer512.61Chemie (UN5)
5H
(A)
waterwater18.0343Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34720.6
Non-Polymers*Number of molecules6
Total formula weight678.7
All*Total formula weight35399.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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