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2F6Y

Protein tyrosine phosphatase 1B with sulfamic acid inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase, non-receptor type 1polymer29834720.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
3C, D, E, F, G
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
PubChem (312)
4H
(A)
3(R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTERnon-polymer385.41Chemie (ENT)
PubChem (22645990)
PubChem (5327152)
PubChem (5327155)
5I
(A)
waterwater18.0326Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34720.6
Non-Polymers*Number of molecules7
Total formula weight587.0
All*Total formula weight35307.6
*Water molecules are not included.

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PDB entries from 2026-05-13

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