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2F6W

Protein tyrosine phosphatase 1B with sulfamic acid inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase, non-receptor type 1polymer29834720.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C, D, E, F, G
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
4H
(A)
(2-METHYL-5-PHENYL-2H-PYRAZOL-3-YL)-SULFAMIC ACIDnon-polymer253.31Chemie (UN3)
5I
(A)
waterwater18.0327Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34720.6
Non-Polymers*Number of molecules7
Total formula weight454.8
All*Total formula weight35175.4
*Water molecules are not included.

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PDB entries from 2025-07-02

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