2F6Q

The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Peroxisomal 3,2-trans-enoyl-CoA isomerase	polymer	280	31351.8	3	UniProt (O75521) Pfam (PF00378) In PDB	Homo sapiens (human)	Dodecenoyl-CoA isomerase, Delta3,delta2-enoyl-CoA isomerase, D3,D2-enoyl-CoA isomerase, DBI-related protein 1, DRS-1, Hepatocellular carcinoma-associated antigen 88
2	B	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
3		water	water		18.0	133	Chemie (HOH)

Sequence modifications

A, B, C: 108 - 364 (UniProt: O75521)

PDB	External Database	Details
Mse -22	-	CLONING ARTIFACT
His -21	-	EXPRESSION TAG
His -20	-	EXPRESSION TAG
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
His -16	-	EXPRESSION TAG
Ser -15	-	CLONING ARTIFACT
Ser -14	-	CLONING ARTIFACT
Gly -13	-	CLONING ARTIFACT
Val -12	-	CLONING ARTIFACT
Asp -11	-	CLONING ARTIFACT
Leu -10	-	CLONING ARTIFACT
Gly -9	-	CLONING ARTIFACT
Thr -8	-	CLONING ARTIFACT
Glu -7	-	CLONING ARTIFACT
Asn -6	-	CLONING ARTIFACT
Leu -5	-	CLONING ARTIFACT
Tyr -4	-	CLONING ARTIFACT
Phe -3	-	CLONING ARTIFACT
Gln -2	-	CLONING ARTIFACT
Ser -1	-	CLONING ARTIFACT
Mse 0	-	CLONING ARTIFACT
Mse 124	Met 119	MODIFIED RESIDUE
Mse 138	Met 133	MODIFIED RESIDUE
Mse 143	Met 138	MODIFIED RESIDUE
Mse 261	Met 256	MODIFIED RESIDUE
Mse 269	Met 264	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	94055.3
Non-Polymers*	Number of molecules	1
	Total formula weight	122.1
All*	Total formula weight	94177.4

*Water molecules are not included.