2F66
Structure of the ESCRT-I endosomal trafficking complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease | polymer | 65 | 7550.7 | 2 | UniProt (P25604) Pfam (PF09454) | Saccharomyces cerevisiae (baker's yeast) | Vacuolar protein sorting-associated protein VPS23 |
| 2 | B, E (B, E) | Vacuolar protein sorting-associated protein VPS28 | polymer | 116 | 13296.8 | 2 | UniProt (Q02767) Pfam (PF03997) | Saccharomyces cerevisiae (baker's yeast) | |
| 3 | C, F (C, F) | Protein SRN2 | polymer | 82 | 9833.9 | 2 | UniProt (Q99176) Pfam (PF07200) | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | G, H (B, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, D: 322 - 385 (UniProt: P25604)
B, E: 15 - 125 (UniProt: Q02767)
| PDB | External Database | Details |
|---|---|---|
| Met 321 | - | cloning artifact |
| Ala 344 | Cys 344 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | cloning artifact |
| Ala 10 | - | cloning artifact |
| Met 11 | - | cloning artifact |
| Ala 101 | Cys 101 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 61362.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 61554.8 |
