2F60

Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (K)	Pyruvate dehydrogenase protein X component	polymer	64	7150.2	1	UniProt (O00330) Pfam (PF02817)	Homo sapiens (human)	Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, Lipoyl-containing pyruvate dehydrogenase complex component X, E3-binding protein, E3BP, proX
2	B, C (K)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	D (K)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

K: 120 - 177 (UniProt: O00330)

PDB	External Database	Details
Gly 120	Lys 173	engineered mutation
Leu 176	Thr 229	engineered mutation
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	7150.2
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	7334.3

*Water molecules are not included.