2F38
Crystal structure of prostaglandin F synathase containing bimatoprost
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aldo-keto reductase family 1 member C3 | polymer | 323 | 36896.2 | 1 | UniProt (P42330) Pfam (PF00248) | Homo sapiens (human) | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, 3-alpha-hydroxysteroid dehydrogenase type 2, 3-alpha-HSD type 2, 3-alpha-HSD type II, brain, Prostaglandin F synthase, PGFS, Estradiol 17-beta-dehydrogenase, 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-HSD 5, Chlordecone reductase homolog HAKRb, HA1753, Dihydrodiol dehydrogenase type I, Dihydrodiol dehydrogenase 3, DD3, DD-3 |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | (5Z)-7-{(1R,2R,3R,5S)-3,5-DIHYDROXY-2-[(1E,3S)-3-HYDROXY-5-PHENYLPENT-1-ENYL]CYCLOPENTYL}-N-ETHYLHEPT-5-ENAMIDE | non-polymer | 415.6 | 1 | Chemie (15M) | |||
| 4 | D (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36896.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1159.0 | |
| All* | Total formula weight | 38055.2 |
