2F18
GOLGI ALPHA-MANNOSIDASE II complex with (2R,3R,4S)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alpha-mannosidase II | polymer | 1045 | 119701.6 | 1 | GenBank (517481) Pfam (PF01074) Pfam (PF09261) Pfam (PF21260) Pfam (PF07748) Pfam (PF18230) UniProt (by SIFTS) (Q24451) In PDB | Drosophila melanogaster (fruit fly) | Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A | (2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL | non-polymer | 252.3 | 1 | Chemie (GB1) | |||
| 6 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 7 | water | water | 18.0 | 1172 | Chemie (HOH) |
Sequence modifications
A: 13 - 1045 (GenBank: 517481)
| PDB | External Database | Details |
|---|---|---|
| Arg 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Glu 11 | - | expression tag |
| Phe 12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 119701.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 752.1 | |
| All* | Total formula weight | 120453.7 |
