2EU0

The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tyrosine-protein kinase ITK/TSK	polymer	109	12560.2	1	UniProt (Q03526) Pfam (PF00017)	Mus musculus (house mouse)	T-cell-specific kinase, IL-2-inducible T-cell kinase, Kinase EMT, Kinase TLK, Itk
2	B (B)	Lymphocyte cytosolic protein 2 phosphopeptide fragment	polymer	8	794.7	1	UniProt (Q60787)		SH2 domain-containing leucocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76

Sequence modifications

A: 4 - 110 (UniProt: Q03526)

PDB	External Database	Details
Gly 111	-	cloning artifact

B: 119 - 124 (UniProt: Q60787)

PDB	External Database	Details
Ptr 121	Tyr 145	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13355.0
All*	Total formula weight	13355.0

*Water molecules are not included.