2EST
Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | ELASTASE | polymer | 240 | 25928.0 | 1 | UniProt (P00772) Pfam (PF00089) | Sus scrofa (pig) | |
| 2 | B (E) | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide | non-polymer | 457.4 | 1 | BIRD (PRD_000418) Chemie (2Z5) | |||
| 3 | C (E) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (E) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
E: 16 - 245 (UniProt: P00772)
| PDB | External Database | Details |
|---|---|---|
| Asn 77 | Asp 92 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25928.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 553.5 | |
| All* | Total formula weight | 26481.5 |
