2EIK
Cadmium ion binding structure of bovine heart cytochrome C oxidase in the fully reduced state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N (A, N) | Cytochrome c oxidase subunit 1 | polymer | 514 | 57093.9 | 2 | UniProt (P00396) Pfam (PF00115) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide I |
| 2 | B, O (B, O) | Cytochrome c oxidase subunit 2 | polymer | 227 | 26068.4 | 2 | UniProt (P68530) Pfam (PF02790) Pfam (PF00116) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide II |
| 3 | C, P (C, P) | Cytochrome c oxidase subunit 3 | polymer | 261 | 29957.6 | 2 | UniProt (P00415) Pfam (PF00510) | Bos taurus (cattle) | Cytochrome c oxidase polypeptide III |
| 4 | D, Q (D, Q) | Cytochrome c oxidase subunit 4 isoform 1 | polymer | 147 | 17179.6 | 2 | UniProt (P00423) Pfam (PF02936) | Bos taurus (cattle) | Cytochrome c oxidase subunit IV isoform 1, COX IV-1, Cytochrome c oxidase polypeptide IV |
| 5 | E, R (E, R) | Cytochrome c oxidase polypeptide Va | polymer | 109 | 12453.1 | 2 | UniProt (P00426) Pfam (PF02284) | Bos taurus (cattle) | |
| 6 | F, S (F, S) | Cytochrome c oxidase polypeptide Vb | polymer | 98 | 10684.0 | 2 | UniProt (P00428) Pfam (PF01215) | Bos taurus (cattle) | VI |
| 7 | G, T (G, T) | Cytochrome c oxidase polypeptide VIa-heart | polymer | 85 | 9629.8 | 2 | UniProt (P07471) Pfam (PF02046) | Bos taurus (cattle) | COXVIAH, Polypeptide VIb |
| 8 | H, U (H, U) | Cytochrome c oxidase subunit VIb isoform 1 | polymer | 85 | 10039.2 | 2 | UniProt (P00429) Pfam (PF02297) | Bos taurus (cattle) | COX VIb-1, Cytochrome c oxidase polypeptide VII, Cytochrome c oxidase subunit AED |
| 9 | I, V (I, V) | Cytochrome c oxidase polypeptide VIc | polymer | 73 | 8537.0 | 2 | UniProt (P04038) Pfam (PF02937) | Bos taurus (cattle) | STA |
| 10 | J, W (J, W) | Cytochrome c oxidase polypeptide VIIa-heart | polymer | 59 | 6682.7 | 2 | UniProt (P07470) Pfam (PF02238) | Bos taurus (cattle) | Cytochrome c oxidase subunit VIIa-H, COX VIIa-M, VIIIC |
| 11 | K, X (K, X) | Cytochrome c oxidase polypeptide VIIb | polymer | 56 | 6365.2 | 2 | UniProt (P13183) Pfam (PF05392) | Bos taurus (cattle) | IHQ |
| 12 | L, Y (L, Y) | Cytochrome c oxidase polypeptide VIIc | polymer | 47 | 5449.4 | 2 | UniProt (P00430) Pfam (PF02935) | Bos taurus (cattle) | VIIIA |
| 13 | M, Z (M, Z) | Cytochrome c oxidase polypeptide VIII-heart | polymer | 46 | 4967.8 | 2 | UniProt (P10175) Pfam (PF02285) | Bos taurus (cattle) | Cytochrome c oxidase subunit 8-1, VIIIb, IX |
| 14 | AA, DB (A, N) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) PubChem (27099) | |||
| 15 | BA, EB (A, N) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 16 | CA, FB (A, N) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 17 | DA, GB, OA, QB, RB... (A, N, C, P, E) | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) PubChem (31193) | |||
| 18 | EA, FA, HB, IB (A, N) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 19 | BB, EC, GA, HA, JB... (L, Y, A, N, Q) | TRISTEAROYLGLYCEROL | non-polymer | 891.5 | 6 | Chemie (TGL) PubChem (11146) | |||
| 20 | IA, JA, KB, LB, SA... (A, N, C, P) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 8 | Chemie (PGV) PubChem (21158857) PubChem (73746220) PubChem (5289145) PubChem (162368821) PubChem (163029036) | |||
| 21 | KA, MB (B, O) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 22 | LA, OB (B, O) | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) PubChem (46936343) PubChem (53962049) PubChem (5289212) PubChem (5313188) PubChem (5313190) PubChem (124586127) PubChem (122219) PubChem (446962) PubChem (5313189) PubChem (5313191) | |||
| 23 | AB, DC, MA, NB, PA... (J, W, B, O, C...) | CHOLIC ACID | non-polymer | 408.6 | 8 | Chemie (CHD) PubChem (16401672) PubChem (16758100) PubChem (18528842) PubChem (20638765) PubChem (23636694) PubChem (23640631) PubChem (23876184) PubChem (24836753) PubChem (24883735) PubChem (43835083) PubChem (44135469) PubChem (44629918) PubChem (44657327) PubChem (45114537) PubChem (45382168) PubChem (46397523) PubChem (46783697) PubChem (49791911) PubChem (49796810) PubChem (50989873) PubChem (51432410) PubChem (51546373) PubChem (16401251) PubChem (21139644) PubChem (53298695) PubChem (1762378) PubChem (44339334) PubChem (46780112) PubChem (53393606) PubChem (53477699) PubChem (59130005) PubChem (59381614) PubChem (59903914) PubChem (67122255) PubChem (69904012) PubChem (57937243) PubChem (130213) PubChem (145883) PubChem (70866085) PubChem (71001249) PubChem (239672) PubChem (71314856) PubChem (71752895) PubChem (58133002) PubChem (58582306) PubChem (74765127) PubChem (89830646) PubChem (91128541) PubChem (58984417) PubChem (59032051) PubChem (5283876) PubChem (5283879) PubChem (5283880) PubChem (5283872) PubChem (5283874) PubChem (98044963) PubChem (59316662) PubChem (99565617) PubChem (59877711) PubChem (59963674) PubChem (59997751) PubChem (60076012) PubChem (60098994) PubChem (60114995) PubChem (66678354) PubChem (122645815) PubChem (124161889) PubChem (124318072) PubChem (124488681) PubChem (125037036) PubChem (126577457) PubChem (129274856) PubChem (129274855) PubChem (129359810) PubChem (68097396) PubChem (68131418) PubChem (68318251) PubChem (68338620) PubChem (68372213) PubChem (71260265) PubChem (70649328) PubChem (133135020) PubChem (133126746) PubChem (11350342) PubChem (70824975) PubChem (70930320) PubChem (70930789) PubChem (70960845) PubChem (303) PubChem (12303168) PubChem (6676) PubChem (13020196) PubChem (122340) PubChem (91810856) PubChem (160636) PubChem (221493) PubChem (376829) PubChem (439520) PubChem (440427) PubChem (162771689) PubChem (99564899) PubChem (99565857) PubChem (163059393) PubChem (163059399) PubChem (163059389) PubChem (637625) PubChem (166858402) PubChem (117684834) PubChem (117767695) PubChem (117944573) PubChem (118241311) PubChem (121232934) PubChem (3246132) PubChem (122537896) PubChem (122537897) PubChem (122644681) PubChem (122644923) PubChem (122646384) PubChem (124328806) PubChem (124364505) PubChem (124425250) PubChem (124488680) PubChem (124511215) PubChem (124518077) PubChem (124518078) PubChem (124518446) PubChem (5283869) PubChem (5283870) PubChem (5283871) PubChem (5283873) PubChem (5283875) PubChem (5283877) PubChem (5283878) PubChem (124761950) PubChem (5302608) PubChem (5315844) PubChem (124841930) PubChem (124896923) PubChem (124896924) PubChem (124896925) PubChem (124896926) PubChem (124904187) PubChem (124904188) PubChem (124906682) PubChem (124906683) PubChem (124914603) PubChem (124914604) PubChem (124914605) PubChem (124914606) PubChem (125027431) PubChem (125037037) PubChem (126422551) PubChem (126422552) PubChem (126577461) PubChem (126672319) PubChem (126969154) PubChem (6708709) PubChem (6850901) PubChem (6850905) PubChem (129106816) PubChem (129460958) PubChem (129600748) PubChem (129628082) PubChem (130220803) PubChem (131700165) PubChem (132441695) PubChem (9802771) PubChem (133548348) PubChem (133612061) PubChem (133655733) PubChem (133687870) PubChem (9846429) PubChem (9866174) PubChem (133688934) PubChem (134462403) PubChem (134555902) PubChem (134866321) PubChem (135373095) PubChem (71172094) PubChem (137474142) PubChem (138107312) PubChem (12080557) PubChem (139248576) PubChem (139291795) PubChem (139372812) PubChem (12303167) PubChem (12303172) PubChem (12303175) PubChem (12303178) PubChem (12303180) PubChem (140618124) PubChem (141854542) PubChem (142134118) PubChem (143658950) PubChem (144316980) PubChem (145264188) PubChem (145714625) PubChem (146030145) PubChem (146665897) PubChem (154033190) PubChem (154036252) PubChem (13020205) PubChem (154747009) PubChem (154825357) PubChem (155275443) PubChem (155605940) PubChem (157048615) PubChem (157269375) PubChem (157351909) PubChem (157383333) PubChem (158041002) PubChem (158420924) PubChem (158675416) PubChem (160081178) PubChem (160743345) PubChem (160917187) PubChem (161973449) PubChem (163059390) PubChem (163059391) PubChem (163059392) PubChem (163059394) PubChem (163059395) PubChem (163059396) PubChem (163059397) PubChem (163059398) PubChem (163059400) PubChem (163452349) PubChem (163452350) PubChem (163452351) PubChem (167344826) PubChem (168841979) PubChem (168841990) PubChem (168845540) PubChem (169410142) PubChem (169436432) PubChem (171721516) PubChem (157060709) | |||
| 24 | CB, FC, NA, PB (M, Z, C, P) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 4 | Chemie (DMU) PubChem (24776995) PubChem (45253991) PubChem (45254001) PubChem (16396531) PubChem (24802064) PubChem (45253971) PubChem (49866911) PubChem (56845266) PubChem (58112552) PubChem (95370473) PubChem (98046563) PubChem (59518661) PubChem (5288728) PubChem (101207920) PubChem (126735852) PubChem (70796430) PubChem (70839938) PubChem (71307274) PubChem (95370474) PubChem (95370475) PubChem (95370476) PubChem (98046559) PubChem (98046561) PubChem (100941450) PubChem (100950626) PubChem (102219024) PubChem (118704896) PubChem (168490163) PubChem (3637526) PubChem (123134571) PubChem (5288091) PubChem (124867949) PubChem (124867950) PubChem (124867951) PubChem (124867952) PubChem (126731012) PubChem (126731036) PubChem (126735974) | |||
| 25 | BC, QA, RA, TB, UB... (T, C, P, G) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 6 | Chemie (PEK) PubChem (21158855) PubChem (44552596) PubChem (45253969) PubChem (45253978) PubChem (53301835) PubChem (53652586) PubChem (123132887) PubChem (9546819) PubChem (72280040) PubChem (134812608) PubChem (73659094) PubChem (5289133) PubChem (6426736) PubChem (9546829) PubChem (9546830) PubChem (145998242) PubChem (156613384) PubChem (162679672) | |||
| 26 | CC, UA, XB, YA (T, C, P, G) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 27 | AC, XA (S, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 28 | AD, BD, CD, DD, ED... (U, V, W, X, Y...) | water | water | 18.0 | 1714 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 410215.6 | |
| Non-Polymers* | Number of molecules | 58 |
| Total formula weight | 33214.9 | |
| All* | Total formula weight | 443430.5 |
