2EHL
Crystal structure of Thr146 to Arg mutant of Diphthine synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | diphthine synthase | polymer | 265 | 29669.5 | 2 | UniProt (O58456) | Pyrococcus horikoshii | Diphthamide biosynthesis methyltransferase |
| 2 | C, D, E, F, K... (A, B) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | G (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (177678424) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (6419189) PubChem (52224398) PubChem (57544532) PubChem (164157219) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (126969526) PubChem (71170554) PubChem (129105892) PubChem (13231890) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | H, O, P (A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 3 | Chemie (MES) PubChem (4478249) | |||
| 5 | I, J, Q, R, S... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) PubChem (753) | |||
| 6 | U, V (A, B) | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
| PDB | External Database | Details |
|---|---|---|
| Arg 146 | Thr 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59338.9 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2291.2 | |
| All* | Total formula weight | 61630.1 |






