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2EHL

Crystal structure of Thr146 to Arg mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529669.52UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, F, K...
(A, B)
SULFATE IONnon-polymer96.18Chemie (SO4)
3G
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (25210495)
PubChem (177678424)
PubChem (21125603)
PubChem (25203782)
PubChem (52224400)
PubChem (44361184)
PubChem (46936206)
PubChem (50989525)
PubChem (51380914)
PubChem (6419189)
PubChem (52224398)
PubChem (57544532)
PubChem (164157219)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (118374891)
PubChem (118560068)
PubChem (193)
PubChem (13792)
PubChem (189149)
PubChem (439155)
PubChem (5284331)
PubChem (126969526)
PubChem (71170554)
PubChem (129105892)
PubChem (13231890)
PubChem (143518505)
PubChem (154578335)
PubChem (163054214)
PubChem (163335525)
4H, O, P
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.23Chemie (MES)
PubChem (4478249)
5I, J, Q, R, S...
(A, B)
GLYCEROLnon-polymer92.16Chemie (GOL)
PubChem (753)
6U, V
(A, B)
waterwater18.0678Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Arg 146Thr 146engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59338.9
Non-Polymers*Number of molecules18
Total formula weight2291.2
All*Total formula weight61630.1
*Water molecules are not included.

253795

PDB entries from 2026-05-20

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