2EGN
Crystal Structure of Tamalin PDZ Domain in Complex with mGluR5 C-terminal Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | General receptor for phosphoinositides 1-associated scaffold protein | polymer | 96 | 10643.9 | 1 | UniProt (Q8R4T5) Pfam (PF00595) | Rattus norvegicus (Norway rat) | GRP1-associated scaffold protein, Tamalin, 95 kDa postsynaptic density protein discs-large ZO-1 domain-containing protein, PSD-95 PDZ domain-containing protein |
| 2 | B (B) | mGluR5 C-terminal peptide | polymer | 5 | 479.5 | 1 | Rattus norvegicus (Norway rat) | ||
| 3 | C, D (A, B) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 96 - 189 (UniProt: Q8R4T5)
| PDB | External Database | Details |
|---|---|---|
| Gly 94 | - | cloning artifact |
| Ser 95 | - | cloning artifact |
| Ala 135 | Cys 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 11123.4 | |
| All* | Total formula weight | 11123.4 |
