2EGK

Crystal Structure of Tamalin PDZ-Intrinsic Ligand Fusion Protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	General receptor for phosphoinositides 1-associated scaffold protein	polymer	101	11277.4	4	UniProt (Q8R4T5) Pfam (PF00595)	Rattus norvegicus (Norway rat)	GRP1-associated scaffold protein, Tamalin, 95 kDa postsynaptic density protein discs-large ZO-1 domain-containing protein, PSD-95 PDZ domain-containing protein
2	E, F (B, C)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3	G, H, I, J (A, B, C, D)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B, C, D: 96 - 189 (UniProt: Q8R4T5)

PDB	External Database	Details
Gly 94	-	cloning artifact
Ser 95	-	cloning artifact
Mse 130	Met 130	modified residue
Ala 135	Cys 135	engineered mutation

A, B, C, D: 190 - 194 (UniProt: Q8R4T5)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	45109.7
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	45299.6

*Water molecules are not included.