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2EGB

Crystal structure of Glu140 to Asn mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529598.42UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, F, G...
(A, B)
SULFATE IONnon-polymer96.110Chemie (SO4)
3H
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (193)
PubChem (25210495)
PubChem (13792)
PubChem (177678424)
PubChem (44361184)
PubChem (21125603)
PubChem (46936206)
PubChem (50989525)
PubChem (25203782)
PubChem (51380914)
PubChem (52224398)
PubChem (189149)
PubChem (57544532)
PubChem (439155)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (52224400)
PubChem (5284331)
PubChem (6419189)
PubChem (118374891)
PubChem (118560068)
PubChem (71170554)
PubChem (13231890)
PubChem (164157219)
PubChem (126969526)
PubChem (129105892)
PubChem (143518505)
PubChem (154578335)
PubChem (163054214)
PubChem (163335525)
4I, Q
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
PubChem (4478249)
5J, K, R, S
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
PubChem (753)
6T, U
(A, B)
waterwater18.0559Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Asn 140Glu 140engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59196.7
Non-Polymers*Number of molecules17
Total formula weight2103.9
All*Total formula weight61300.6
*Water molecules are not included.

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PDB entries from 2026-05-13

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