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2EGB

Crystal structure of Glu140 to Asn mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529598.42UniProt (O58456)
Pfam (PF00590)
Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, F, G...
(A, B)
SULFATE IONnon-polymer96.110Chemie (SO4)
3H
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
4I, Q
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
5J, K, R, S
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
6T, U
(A, B)
waterwater18.0559Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Asn 140Glu 140engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59196.7
Non-Polymers*Number of molecules17
Total formula weight2103.9
All*Total formula weight61300.6
*Water molecules are not included.

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PDB entries from 2025-11-19

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