2EFR

Crystal structure of the c-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 1.8 angstroms resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	General control protein GCN4 and Tropomyosin 1 alpha chain	polymer	155	18338.7	4	UniProt (P03069) UniProt (P58772) Pfam (PF07716) Pfam (PF00261)	Saccharomyces cerevisiae (baker's yeast rabbit)
2	E, F, G, H (A, B, C, D)	water	water		18.0	1460	Chemie (HOH)

Sequence modifications

A, B, C, D: 147 - 175 (UniProt: P03069)

PDB	External Database	Details
Met 274	-	expression tag
Lys 275	-	expression tag
Gln 276	-	expression tag
Leu 277	-	expression tag
Glu 278	-	expression tag
Asp 279	-	expression tag
Lys 280	-	expression tag
Val 281	-	expression tag
Glu 282	-	expression tag
Glu 283	-	expression tag
Leu 284	-	expression tag
Leu 285	-	expression tag
Ser 286	-	expression tag
Lys 287	-	expression tag
Asn 288	-	expression tag
Tyr 289	-	expression tag
His 290	-	expression tag
Leu 291	-	expression tag
Glu 292	-	expression tag
Asn 293	-	expression tag
Glu 294	-	expression tag
Val 295	-	expression tag
Ala 296	-	expression tag
Arg 297	-	expression tag
Leu 298	-	expression tag
Lys 299	-	expression tag
Lys 300	-	expression tag
Leu 301	-	expression tag

A, B, C, D: 176 - 273 (UniProt: P58772)

PDB	External Database	Details
Ser 190	Cys 190	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73354.8
All*	Total formula weight	73354.8

*Water molecules are not included.