2E9R
Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3' | polymer | 9 | 2846.8 | 1 | |||
| 2 | B (B) | 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3' | polymer | 6 | 1906.2 | 1 | |||
| 3 | C (X) | RNA-dependent RNA polymerase | polymer | 476 | 53486.7 | 1 | UniProt (Q0QEE1) Pfam (PF00680) UniProt (by SIFTS) (Q9QCE4) | Foot-and-mouth disease virus C-S8c1 | |
| 4 | D (X) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (X) | RIBAVIRIN TRIPHOSPHATE | non-polymer | 484.1 | 1 | Chemie (RTP) | |||
| 6 | F, G, H (A, B, X) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
X: 1 - 470 (UniProt: Q0QEE1)
| PDB | External Database | Details |
|---|---|---|
| Ala 471 | - | cloning artifact |
| Ala 472 | - | cloning artifact |
| Leu 473 | - | cloning artifact |
| Glu 474 | - | cloning artifact |
| His 475 | - | cloning artifact |
| His 476 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58239.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 508.4 | |
| All* | Total formula weight | 58748.1 |
