2E3X
Crystal structure of Russell's viper venom metalloproteinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X-activating enzyme heavy chain | polymer | 427 | 47703.1 | 1 | UniProt (Q7LZ61) Pfam (PF01421) Pfam (PF00200) Pfam (PF08516) | Daboia russellii siamensis | RVV-X heavy chain, Coagulation factor X-activating enzyme alpha-chain, Russellysin |
| 2 | B (B) | Coagulation factor X-activating enzyme light chain 2 | polymer | 134 | 15961.1 | 1 | UniProt (Q4PRD2) Pfam (PF00059) | Daboia russellii siamensis | RVV-X light chain 1, Coagulation factor X-activating enzyme beta-chain, C-type lectin-like protein subunit 1, RVV-X light chain-A |
| 3 | C (C) | Coagulation factor X-activating enzyme light chain 1 | polymer | 122 | 14357.5 | 1 | UniProt (Q4PRD1) Pfam (PF00059) | Daboia russellii siamensis | RVV-X light chain 1, Coagulation factor X-activating enzyme gamma-chain, C-type lectin-like protein subunit 2, RVV-X light chain-B |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (E) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G04854NQ) | |||
| 6 | F, M (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | H, I, J, K, N (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 9 | L (A) | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE | non-polymer | 388.5 | 1 | Chemie (GM6) |
Sequence modifications
A: 1 - 427 (UniProt: Q7LZ61)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | Glu 127 | SEE REMARK 999 |
| - | Thr 273 | SEE REMARK 999 |
| - | Arg 274 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78021.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1096.7 | |
| All* | Total formula weight | 80291.5 |
