2E3V

Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Neural cell adhesion molecule 1, 140 kDa isoform	polymer	122	12842.0	3	UniProt (P13591) Pfam (PF00041) In PDB	Homo sapiens (human)	N-CAM 140, NCAM-140, CD56 antigen, neural cell adhesion molecule, splicing isoform from human muscle culture, clone lambda-4.4
2	A, B, C	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
3	B	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
4	B, C	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	2	Chemie (BTB)
5	C	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6		water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B, C: 10 - 118 (UniProt: P13591)

PDB	External Database	Details
Gly 3	-	EXPRESSION TAG
Ser 4	-	EXPRESSION TAG
Ser 5	-	EXPRESSION TAG
Gly 6	-	EXPRESSION TAG
Ser 7	-	EXPRESSION TAG
Ser 8	-	EXPRESSION TAG
Gly 9	-	EXPRESSION TAG
Arg 109	Gln 599	SEE REMARK 999
Arg 109	Gly 600	SEE REMARK 999
Ser 119	-	EXPRESSION TAG
Gly 120	-	EXPRESSION TAG
Pro 121	-	EXPRESSION TAG
Ser 122	-	EXPRESSION TAG
Ser 123	-	EXPRESSION TAG
Gly 124	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	38525.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1099.3
All*	Total formula weight	39625.2

*Water molecules are not included.