2E1Q
Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Xanthine dehydrogenase/oxidase | polymer | 1333 | 146571.8 | 4 | UniProt (P47989) Pfam (PF00111) Pfam (PF01799) Pfam (PF00941) Pfam (PF03450) Pfam (PF01315) Pfam (PF02738) Pfam (PF20256) | Homo sapiens (human) | Xanthine dehydrogenase, XD, Xanthine oxidase, XO, Xanthine oxidoreductase |
| 2 | E, FA, N, W (A, D, B, C) | BICARBONATE ION | non-polymer | 61.0 | 4 | Chemie (BCT) | |||
| 3 | F, G, GA, HA, O... (A, D, B, C) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 4 | AA, H, I, IA, JA... (C, A, D, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 8 | Chemie (FES) | |||
| 5 | BA, J, KA, S (C, A, D, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 6 | CA, K, LA, T (C, A, D, B) | PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER | non-polymer | 395.4 | 4 | Chemie (MTE) | |||
| 7 | DA, L, MA, U (C, A, D, B) | HYDROXY(DIOXO)MOLYBDENUM | non-polymer | 144.9 | 4 | Chemie (MOM) | |||
| 8 | EA, M, NA, V (C, A, D, B) | 2-HYDROXYBENZOIC ACID | non-polymer | 138.1 | 4 | Chemie (SAL) | |||
| 9 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 949 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 1333 (UniProt: P47989)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Val 803 | Glu 802 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 586287.2 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 7827.1 | |
| All* | Total formula weight | 594114.3 |
