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2E16

Crystal structure of Glu140 to Arg mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Probable diphthine synthasepolymer26529641.42UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, I, J...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
3F
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (193)
PubChem (25210495)
PubChem (13792)
PubChem (177678424)
PubChem (44361184)
PubChem (21125603)
PubChem (46936206)
PubChem (50989525)
PubChem (25203782)
PubChem (51380914)
PubChem (52224398)
PubChem (189149)
PubChem (57544532)
PubChem (439155)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (52224400)
PubChem (5284331)
PubChem (6419189)
PubChem (118374891)
PubChem (118560068)
PubChem (71170554)
PubChem (13231890)
PubChem (164157219)
PubChem (126969526)
PubChem (129105892)
PubChem (143518505)
PubChem (154578335)
PubChem (163054214)
PubChem (163335525)
4G, L
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
PubChem (4478249)
5H, M
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
PubChem (753)
6N, O
(A, B)
waterwater18.0374Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Arg 140Glu 140engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59282.9
Non-Polymers*Number of molecules11
Total formula weight1535.5
All*Total formula weight60818.3
*Water molecules are not included.

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PDB entries from 2026-05-13

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