2E0O
Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonuclease | polymer | 129 | 14705.7 | 2 | UniProt (P07998) Pfam (PF00074) | Homo sapiens (human) | Ribonuclease 1, RNase 1, RNase A, RNase UpI-1, RIB-1, HP-RNase |
| 2 | C, D, E, F, G... (A, B) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 3 | H, I (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | N, O (A, B) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 128 (UniProt: P07998)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Leu 52 | Val 80 | engineered mutation |
| Leu 53 | Asp 81 | engineered mutation |
| Leu 56 | Asn 84 | engineered mutation |
| Leu 59 | Phe 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29411.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1048.8 | |
| All* | Total formula weight | 30460.2 |
