2E0M
Mutant Human Ribonuclease 1 (T24L, Q28L, R31L, R32L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonuclease | polymer | 129 | 14637.6 | 2 | UniProt (P07998) Pfam (PF00074) | Homo sapiens (human) | Ribonuclease 1, RNase 1, RNase A, RNase UpI-1, RIB-1, HP-RNase |
| 2 | C, D, E, F, G... (A, B) | CADMIUM ION | non-polymer | 112.4 | 8 | Chemie (CD) | |||
| 3 | H, I, J, K, L... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) | |||
| 4 | V, W (A, B) | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 128 (UniProt: P07998)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Leu 24 | Thr 52 | engineered mutation |
| Leu 28 | Gln 56 | engineered mutation |
| Leu 31 | Arg 59 | engineered mutation |
| Leu 32 | Arg 60 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29275.2 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1289.3 | |
| All* | Total formula weight | 30564.5 |
