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2DXW

Crystal structure of Glu54 to Lys mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529613.42UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, I, J...
(A, B)
SULFATE IONnon-polymer96.17Chemie (SO4)
3F
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (193)
PubChem (25210495)
PubChem (13792)
PubChem (177678424)
PubChem (44361184)
PubChem (21125603)
PubChem (46936206)
PubChem (50989525)
PubChem (25203782)
PubChem (51380914)
PubChem (52224398)
PubChem (189149)
PubChem (57544532)
PubChem (439155)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (52224400)
PubChem (5284331)
PubChem (6419189)
PubChem (118374891)
PubChem (118560068)
PubChem (71170554)
PubChem (13231890)
PubChem (164157219)
PubChem (126969526)
PubChem (129105892)
PubChem (143518505)
PubChem (154578335)
PubChem (163054214)
PubChem (163335525)
4G, M
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
PubChem (4478249)
5H, N, O, P
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
PubChem (753)
6Q, R
(A, B)
waterwater18.0523Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Lys 54Glu 54engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59226.9
Non-Polymers*Number of molecules14
Total formula weight1815.7
All*Total formula weight61042.6
*Water molecules are not included.

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PDB entries from 2026-05-13

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