2DWB
Aurora-A kinase complexed with AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 6 | polymer | 285 | 33203.4 | 1 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | Aurora-A kinase, Serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, hARK1, Aurora-A, Breast-tumor-amplified kinase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | D (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 122 - 403 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | - | cloning artifact |
| His 120 | - | cloning artifact |
| Mse 121 | - | cloning artifact |
| Mse 300 | Met 300 | modified residue |
| Mse 305 | Met 305 | modified residue |
| Mse 373 | Met 373 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33203.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 602.3 | |
| All* | Total formula weight | 33805.7 |
