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2DV7

Crystal structure of Lys187 to Arg mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529641.42UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, I, J, K
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
3E
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (25210495)
PubChem (44361184)
PubChem (46936206)
PubChem (50989525)
PubChem (51380914)
PubChem (177678424)
PubChem (52224398)
PubChem (21125603)
PubChem (25203782)
PubChem (52224400)
PubChem (57544532)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (6419189)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (193)
PubChem (13792)
PubChem (189149)
PubChem (439155)
PubChem (164157219)
PubChem (118374891)
PubChem (118560068)
PubChem (5284331)
PubChem (126969526)
PubChem (129105892)
PubChem (71170554)
PubChem (143518505)
PubChem (154578335)
PubChem (13231890)
PubChem (163054214)
PubChem (163335525)
4F, L, M
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.23Chemie (MES)
PubChem (4478249)
5G, H, N
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
6O, P
(A, B)
waterwater18.0313Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Arg 187Lys 187engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59282.8
Non-Polymers*Number of molecules12
Total formula weight1726.7
All*Total formula weight61009.5
*Water molecules are not included.

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PDB entries from 2026-03-25

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