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2DV5

Crystal structure of Leu65 to Ala mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529571.32UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, I, J...
(A, B)
SULFATE IONnon-polymer96.17Chemie (SO4)
3F
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (25210495)
PubChem (44361184)
PubChem (46936206)
PubChem (50989525)
PubChem (51380914)
PubChem (177678424)
PubChem (52224398)
PubChem (21125603)
PubChem (25203782)
PubChem (52224400)
PubChem (57544532)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (6419189)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (193)
PubChem (13792)
PubChem (189149)
PubChem (439155)
PubChem (164157219)
PubChem (118374891)
PubChem (118560068)
PubChem (5284331)
PubChem (126969526)
PubChem (129105892)
PubChem (71170554)
PubChem (143518505)
PubChem (154578335)
PubChem (13231890)
PubChem (163054214)
PubChem (163335525)
4G, M
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
PubChem (4478249)
5H, N, O
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
6P, Q
(A, B)
waterwater18.0436Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Ala 65Leu 65engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59142.6
Non-Polymers*Number of molecules13
Total formula weight1723.6
All*Total formula weight60866.2
*Water molecules are not included.

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PDB entries from 2026-03-25

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