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2DV4

Crystal structure of Leu65 to Gln mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529628.32UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, I, J...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
3F
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (25210495)
PubChem (44361184)
PubChem (46936206)
PubChem (50989525)
PubChem (51380914)
PubChem (177678424)
PubChem (52224398)
PubChem (21125603)
PubChem (25203782)
PubChem (52224400)
PubChem (57544532)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (6419189)
PubChem (66805708)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (193)
PubChem (13792)
PubChem (189149)
PubChem (439155)
PubChem (164157219)
PubChem (118374891)
PubChem (118560068)
PubChem (5284331)
PubChem (126969526)
PubChem (129105892)
PubChem (71170554)
PubChem (143518505)
PubChem (154578335)
PubChem (13231890)
PubChem (163054214)
PubChem (163335525)
4G, M, N
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.23Chemie (MES)
PubChem (4478249)
5H, O, P
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
6L
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
PubChem (312)
7Q, R
(A, B)
waterwater18.0363Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Gln 65Leu 65engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59256.7
Non-Polymers*Number of molecules14
Total formula weight1858.2
All*Total formula weight61114.9
*Water molecules are not included.

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PDB entries from 2026-03-25

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