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2DT7

Solution structure of the second SURP domain of human splicing factor SF3a120 in complex with a fragment of human splicing factor SF3a60

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Splicing factor 3A subunit 3polymer384452.11UniProt (Q12874)
Pfam (PF12108)
Homo sapiens (human)Spliceosome-associated protein 61, SAP 61, SF3a60
2B
(B)
Splicing factor 3 subunit 1polymer859990.31UniProt (Q15459)
Pfam (PF01805)
Homo sapiens (human)Spliceosome-associated protein 114, SAP 114, SF3a120
Sequence modifications
A: 71 - 107 (UniProt: Q12874)
PDBExternal DatabaseDetails
Gly 70-cloning artifact
B: 134 - 217 (UniProt: Q15459)
PDBExternal DatabaseDetails
Gly 133-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14442.4
All*Total formula weight14442.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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