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2DSH

Crystal structure of Lys26 to Tyr mutant of Diphthine synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
diphthine synthasepolymer26529647.42UniProt (O58456)Pyrococcus horikoshiiDiphthamide biosynthesis methyltransferase
2C, D, E, J, K...
(A, B)
SULFATE IONnon-polymer96.17Chemie (SO4)
3F
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
PubChem (16760024)
PubChem (193)
PubChem (13792)
PubChem (177678424)
PubChem (189149)
PubChem (439155)
PubChem (25210495)
PubChem (21125603)
PubChem (44361184)
PubChem (25203782)
PubChem (46936206)
PubChem (50989525)
PubChem (51380914)
PubChem (52224398)
PubChem (57544532)
PubChem (52224400)
PubChem (59046843)
PubChem (59170628)
PubChem (59576228)
PubChem (66805708)
PubChem (5284331)
PubChem (70689219)
PubChem (70702054)
PubChem (70832431)
PubChem (71170554)
PubChem (13231890)
PubChem (6419189)
PubChem (118374891)
PubChem (118560068)
PubChem (126969526)
PubChem (129105892)
PubChem (164157219)
PubChem (143518505)
PubChem (154578335)
PubChem (163054214)
PubChem (163335525)
4G, N, O
(A, B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.23Chemie (MES)
PubChem (4478249)
5H, I, P
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
6Q, R
(A, B)
waterwater18.0510Chemie (HOH)
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
PDBExternal DatabaseDetails
Tyr 26Lys 26engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59294.7
Non-Polymers*Number of molecules14
Total formula weight1918.8
All*Total formula weight61213.6
*Water molecules are not included.

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PDB entries from 2026-04-01

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