2DR0
Crystal structure of human carboxylesterase in complex with taurocholate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Liver carboxylesterase 1 | polymer | 542 | 59787.5 | 3 | UniProt (P23141) Pfam (PF00135) | Homo sapiens (human) | Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, TGH, Egasyn |
| 2 | D, J, P (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E, K, Q (A, B, C) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 3 | Chemie (SIA) | |||
| 4 | F, G, L, M, R... (A, B, C) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | H, I, N, O, T... (A, B, C) | TAUROCHOLIC ACID | non-polymer | 515.7 | 6 | Chemie (TCH) PubChem (8959) PubChem (440567) PubChem (3083030) PubChem (5321637) PubChem (6604033) PubChem (9829087) PubChem (9871180) PubChem (12359086) PubChem (12359094) PubChem (15038755) PubChem (16759980) PubChem (17754196) PubChem (21252258) PubChem (21252259) PubChem (23638032) PubChem (23638462) PubChem (24211913) PubChem (24883685) PubChem (24883686) PubChem (43835311) PubChem (44263378) PubChem (18635674) PubChem (23638159) PubChem (46936954) PubChem (46783527) PubChem (49874123) PubChem (57696923) PubChem (176575120) PubChem (5247) PubChem (6675) PubChem (444349) PubChem (53300296) PubChem (97043673) PubChem (98619445) PubChem (54422651) PubChem (54422653) PubChem (6851757) PubChem (124364479) PubChem (124837206) PubChem (56846334) PubChem (9892729) PubChem (126969227) PubChem (57348502) PubChem (11957444) PubChem (12359085) PubChem (13020211) PubChem (162910408) PubChem (172909646) PubChem (73759780) PubChem (89830645) PubChem (97043674) PubChem (99565400) PubChem (99565401) PubChem (99565642) PubChem (99566013) PubChem (121540598) PubChem (124364480) PubChem (124422686) PubChem (124511137) PubChem (124518535) PubChem (124897363) PubChem (124897364) PubChem (124897365) PubChem (124897366) PubChem (125040592) PubChem (125040593) PubChem (125040594) PubChem (125040595) PubChem (131632375) PubChem (133564570) PubChem (133687180) PubChem (137705086) PubChem (138114967) PubChem (139292118) PubChem (141936888) PubChem (142009958) PubChem (142492777) PubChem (145740517) PubChem (145806620) PubChem (155288797) PubChem (158819942) PubChem (162477955) PubChem (162910409) PubChem (163199393) PubChem (164051294) | |||
| 6 | V, W, X (A, B, C) | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A, B, C: 1019 - 1561 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 179362.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 5262.0 | |
| All* | Total formula weight | 184624.6 |
