2DR0
Crystal structure of human carboxylesterase in complex with taurocholate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Liver carboxylesterase 1 | polymer | 542 | 59787.5 | 3 | UniProt (P23141) Pfam (PF00135) | Homo sapiens (human) | Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, TGH, Egasyn |
| 2 | D, J, P (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E, K, Q (A, B, C) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 3 | Chemie (SIA) | |||
| 4 | F, G, L, M, R... (A, B, C) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | H, I, N, O, T... (A, B, C) | TAUROCHOLIC ACID | non-polymer | 515.7 | 6 | Chemie (TCH) | |||
| 6 | V, W, X (A, B, C) | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A, B, C: 1019 - 1561 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 179362.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 5262.0 | |
| All* | Total formula weight | 184624.6 |
