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2DPK

The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium/calcium exchanger 1polymer15216692.31UniProt (P23685)
Pfam (PF03160)
Canis lupus familiaris (dog)CBD1, Na+/Ca2+ exchange protein 1
2B, C, D, E
(A)
CALCIUM IONnon-polymer40.14Chemie (CA)
3F
(A)
GUANIDINEnon-polymer59.11Chemie (GAI)
4G
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
5H
(A)
waterwater18.017Chemie (HOH)
Sequence modifications
A: 370 - 509 (UniProt: P23685)
PDBExternal DatabaseDetails
Met 358-expression tag
Arg 359-expression tag
Gly 360-expression tag
Ser 361-expression tag
His 362-expression tag
His 363-expression tag
His 364-expression tag
His 365-expression tag
His 366-expression tag
His 367-expression tag
Gly 368-expression tag
Ile 369-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16692.3
Non-Polymers*Number of molecules6
Total formula weight457.7
All*Total formula weight17149.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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