2DOH
The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Angiostatin | polymer | 234 | 26757.6 | 1 | UniProt (P00747) Pfam (PF00051) In PDB | Homo sapiens (human) | |
| 2 | C | Plasminogen-binding group A streptococcal M-like protein PAM | polymer | 30 | 3619.0 | 1 | Pfam (PF12107) UniProt (by SIFTS) (P49054) In PDB | Fragment | |
| 3 | X | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 1 | Chemie (DIO) | |||
| 4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
X: 81 - 314 (UniProt: P00747)
| PDB | External Database | Details |
|---|---|---|
| Glu 289 | Asn 308 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30376.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 88.1 | |
| All* | Total formula weight | 30464.7 |
