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2DJL

Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with succinate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
dihydroorotate dehydrogenasepolymer31434214.52GenBank (81295307)
Pfam (PF01180)
UniProt (by SIFTS) (Q4D3W2)
Trypanosoma cruzi
2C
(A)
COBALT HEXAMMINE(III)non-polymer161.11Chemie (NCO)
3D, J
(A, B)
FLAVIN MONONUCLEOTIDEnon-polymer456.32Chemie (FMN)
4E, K
(A, B)
SUCCINIC ACIDnon-polymer118.12Chemie (SIN)
5F, G, H, I, L
(A, B)
GLYCEROLnon-polymer92.15Chemie (GOL)
6M, N
(A, B)
waterwater18.0695Chemie (HOH)
Sequence modifications
A, B: -1 - 312 (GenBank: 81295307)
PDBExternal DatabaseDetails
Cys 24Ser 26conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68429.0
Non-Polymers*Number of molecules10
Total formula weight1770.5
All*Total formula weight70199.4
*Water molecules are not included.

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PDB entries from 2025-11-19

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