2DEX
Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Protein-arginine deiminase type IV | polymer | 671 | 74933.8 | 1 | UniProt (Q9UM07) Pfam (PF08526) Pfam (PF08527) Pfam (PF03068) | Homo sapiens (human) | Peptidylarginine deiminase IV, HL-60 PAD, peptidylarginine deiminase 4 |
| 2 | B (A) | 10-mer peptide from histone H3 | polymer | 10 | 1128.4 | 1 | |||
| 3 | C, D, E, F, G (X) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | H, I, J (X) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | K, L (X, A) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
X: 1 - 663 (UniProt: Q9UM07)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | cloning artifact |
| Pro -6 | - | cloning artifact |
| Leu -5 | - | cloning artifact |
| Gly -4 | - | cloning artifact |
| Ser -3 | - | cloning artifact |
| Pro -2 | - | cloning artifact |
| Glu -1 | - | cloning artifact |
| Phe 0 | - | cloning artifact |
| Ala 645 | Cys 645 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76062.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 488.6 | |
| All* | Total formula weight | 76550.8 |
