2DDY
Solution Structure of Matrilysin (MMP-7) Complexed to Constraint Conformational Sulfonamide Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Matrilysin | polymer | 173 | 19157.5 | 1 | UniProt (P09237) Pfam (PF00413) In PDB | Homo sapiens (human) | Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP-7, Matrin |
2 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A | (1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE | non-polymer | 408.4 | 1 | Chemie (MDW) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19157.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 619.4 | |
All* | Total formula weight | 19776.9 |