2DCM

The Crystal Structure of S603A Mutated Prolyl Tripeptidyl Aminopeptidase Complexed with Substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	dipeptidyl aminopeptidase IV, putative	polymer	706	79588.8	1	UniProt (Q7MUW6) Pfam (PF00930) Pfam (PF00326)	Porphyromonas gingivalis	prolyl tripeptidyl aminopeptidase
2	B (A)	GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE	non-polymer		368.4	1	Chemie (GA0)
3	C (A)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

A: 39 - 732 (UniProt: Q7MUW6)

PDB	External Database	Details
Met 27	-	expression tag
Arg 28	-	expression tag
Gly 29	-	expression tag
Ser 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Gly 37	-	expression tag
Ser 38	-	expression tag
Ala 603	Ser 603	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	79588.8
Non-Polymers*	Number of molecules	1
	Total formula weight	368.4
All*	Total formula weight	79957.2

*Water molecules are not included.