2D7R
Crystal structure of pp-GalNAc-T10 complexed with GalNAc-Ser on lectin domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polypeptide N-acetylgalactosaminyltransferase 10 | polymer | 570 | 65472.3 | 1 | UniProt (Q86SR1) Pfam (PF00535) Pfam (PF00652) | Homo sapiens (human) | Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, Polypeptide GalNAc transferase 10, GalNAc-T10, pp-GaNTase 10 |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (NGA) | |||
| 5 | F (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 6 | G (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 7 | H (A) | SERINE | non-polymer | 105.1 | 1 | Chemie (SER) | |||
| 8 | I (A) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 9 | J (A) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 40 - 603 (UniProt: Q86SR1)
| PDB | External Database | Details |
|---|---|---|
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65472.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1449.0 | |
| All* | Total formula weight | 67345.7 |
