2D7I

Crystal structure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polypeptide N-acetylgalactosaminyltransferase 10	polymer	570	65472.3	1	UniProt (Q86SR1) Pfam (PF00535) Pfam (PF00652)	Homo sapiens (human)	Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, Polypeptide GalNAc transferase 10, GalNAc-T10, pp-GaNTase 10
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	D (A)	2-acetamido-2-deoxy-beta-D-galactopyranose	non-polymer		221.2	1	Chemie (NGA)
5	F (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN) PubChem (27854)
6	G (A)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (3084486) PubChem (60098857) PubChem (57448939) PubChem (6101632) PubChem (6604175) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (11811538) PubChem (93088131) PubChem (93630083) PubChem (12049241)
7	H (A)	water	water		18.0	237	Chemie (HOH)

Sequence modifications

A: 40 - 603 (UniProt: Q86SR1)

PDB	External Database	Details
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65472.3
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1122.7
All*	Total formula weight	67019.4

*Water molecules are not included.