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2D3Z

X-ray crystal structure of hepatitis C virus RNA-dependent RNA polymerase in complex with non-nucleoside analogue inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
polyproteinpolymer57063274.62UniProt (Q99AU2)
Pfam (PF00998)
Hepatitis C virusNS5B
2C, D
(A, B)
5-(4-FLUOROPHENYL)-3-{[(4-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACIDnon-polymer391.42Chemie (FIH)
3E, F
(A, B)
waterwater18.01291Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight126549.1
Non-Polymers*Number of molecules2
Total formula weight782.9
All*Total formula weight127332.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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