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2D11

Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Radixinpolymer31236924.64UniProt (P26043)
Pfam (PF09379)
Pfam (PF00373)
Pfam (PF09380)
Mus musculus (house mouse)ESP10
2E, F, G, H
(E, F, G, H)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2polymer283517.14UniProt (Q15599)
Pfam (PF09007)
NHERF-2, Tyrosine kinase activator protein 1, TKA-1, SRY interacting protein 1, SIP- 1, Solute carrier family 9 isoform A3 regulatory factor 2, NHE3 kinase A regulatory protein E3KARP, Sodium-hydrogen exchanger regulatory factor 2
3I, J, K, L, M
(A, B, C, D, E)
waterwater18.0163Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 310 (UniProt: P26043)
PDBExternal DatabaseDetails
Gly -1-cloning artifact
Ser 0-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight161766.7
All*Total formula weight161766.7
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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