2D0T
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Indoleamine 2,3-dioxygenase | polymer | 406 | 45666.5 | 2 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (human) | IDO, Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | C, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, H (A, B) | 4-PHENYL-1H-IMIDAZOLE | non-polymer | 144.2 | 2 | Chemie (PIM) | |||
| 4 | E, F, I, J (A, B) | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 4 | Chemie (NHE) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 403 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91333.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2350.5 | |
| All* | Total formula weight | 93683.4 |
