2D0N
Crystal structure of the C-terminal SH3 domain of the adaptor protein GADS in complex with SLP-76 motif peptide reveals a unique SH3-SH3 interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GRB2-related adaptor protein 2 | polymer | 59 | 6719.5 | 2 | UniProt (O89100) Pfam (PF00018) | Mus musculus (house mouse) | GADS protein, Growth factor receptor binding protein, GRBLG, GRB-2-like protein, GRB2L, Hematopoietic cell-associated adaptor protein GrpL, GRB-2-related monocytic adapter protein, Monocytic adapter, MONA, Adapter protein GRID |
| 2 | B, D (B, D) | SLP-76 binding peptide | polymer | 9 | 1002.1 | 2 | |||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, C: 267 - 322 (UniProt: O89100)
| PDB | External Database | Details |
|---|---|---|
| Gly 264 | - | cloning artifact |
| Ser 265 | - | cloning artifact |
| Pro 266 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 15443.2 | |
| All* | Total formula weight | 15443.2 |
